1- Arsenic trioxide
for remission induction in acute promyelocytic leukemia (APL); a
pilot study
So far, seven
patients (5 female and 2 male) have undergone this treatment
protocol and all of them responded completely.
Minimum and maximum
age of patients was 21 and 56 years respectively. No complication
was seen during the treatment course. Two patients also received
consolidation therapy.
2-
Clinical course of breast cancer in patients under 35 years old,
between 35 to 50 years old and over 50 years old on the basis of
clinical, biological and pathological characteristics
Necessary
information about nearly 400 patients is gathered till now under
this study.
3-
Construction of genomic DNA bank for patients with hematopoetic
malignancies.
Construction of a special laboratory for DNA extraction from
patients with hematopoetic malignancies was performed in 1382 at
Taleghani Hospital in Kermanshah. It was done in collaboration
with the Hematology-Oncology and BMT Research Center in Shariati
Hospital. In this procedure, blood sample (10 cc) was obtained and
the DNA content was extracted by salting out method; one sample
was sent to Shariati Hospital and the other was retained at
Taleghani Hospital. Already, DNA from 60 patients has been
extracted and maintained.
4-
Phase 2 study of Irinotecan, 5-FU and Leucovorin in advanced
gastric cancer
Till now,
11 patients entered the study at Taleghani Hospital in Kermanshah;
in 9 cases, objective and subjective response to treatment was
seen. One case did not respond to regimen and one patient died. Of
course, we can not judge about the effectiveness of treatment
until the end of the study.
